Valentina BucherPhD candidate
Pre-clinical and clinical studies of cerebral complications in preeclampsia
Valentina is a PhD candidate with Lina Bergman at the University of Gothenburg. She has received her Master’s degree from the University of Tübingen in Germany where she studied Molecular Medicine.
In her PhD project, Valentina focuses on pre-clinical and clinical studies of cerebral complications in preeclampsia. Cerebral complications secondary to preeclampsia are among the most common causes to direct maternal mortality. The cause behind acute cerebral complications is not fully elucidated. Therefore, Valentina studies neuroinflammatory and neurovascular mechanisms in pre-clinical in-vitro and in-vivo settings. An improved understanding of this could lead to development of more efficient treatment and hopefully a better short- and long-term prognosis for these women.
Additionally, there is a lack of reliable predictors of women at risk of cerebral complications. Valentina evaluates existing predictors for complications in preeclampsia in a systematic review and meta-analysis and evaluates angiogenic biomarkers in plasma in women with newly diagnosed preeclampsia with the aim to identify reliable predictors for end-organ complications.