Ralf DechendMD, Cardiology, Hypertension Specialist, Professor
Vascular Remodeling during and post preeclampsia (experimental and clinical)
Placenta Cell atlas: single cell and spatial transciptomics for preeclampsia
Ralf Dechend is a specialist in internal medicine since 2001 and cardiology and is currently working as a professor of internal medicine at HELIOS Clinic Berlin Buch and the Experimental and Clinical Research Center, Charité and Max-Delbrueck Center for Molecular Medicine in Berlin. With his close friend Prof. Dominik N Mueller he is co-sharing the research group interested in hypertension, immunology and the micromilieu. Ralf has a long standing interest in understanding the molecular mechanisms leading to preeclampsia, hypertension and endothelial dysfunction. His lab described the activating autoantibodies against the AT-1 receptor. Recently he became interested in understanding the cardiovascular burden post preeclampsia, including the remodeling process in the 4th trimenon. Recently his lab started the endeavor to build a placenta cell atlas using computational analysis of single nuclei sequencing and spatial transcriptomics and proteomics of the placenta. One major goal is to understand the different placental signatures in preeclampsia and eclampsia of low and middle income countries compared to high income countries.