Carlos Escudero OrozcoMD, PhD (Biomedical Sciences), Full-professor Universidad del Bio Bio
In vitro studies of the vasculature in preeclampsia with material from PROVE, GO PROVE and UPMOST focusing on brain endothelial cells
Current research projects
- PI (2020-2024). Role of pro-migratory activation of VEGFR2 in the brain angiogenesis and its potential implication in learning and memory of offspring born to preeclampsia. Fondecyt regular 1200250.
- Co-PI (2019-2021). Placental growth factor and cerebral blood vessel formation in offspring from preeclamptic pregnancies. Evelyn Lara (PI). Fondecyt posdoct. 3190475.
- Co-I (2020-2023). Saving Maternal Brains. Mobility Grants for Internationalisation programme. STINT (cooperation in Research and Higher Education). Anna-Karin Wikström (PI).
- Co-I (2019-2021). Preeclampsia Obstetric Adverse Events (PROVE study). Lina Bergman (PI). Swedish Society of Medicine, number SLS-878741.
- Co-I (2019-2021). Saving maternal brains. Ana-Karin Wikstrom (PI). Hjärnfonden.
Carlos Escudero is a vascular physiologist. His current area of interest is to understand the potential negative consequences of preeclampsia in the brain vascular formation and the integrity of the blood-brain barrier in mother and babies exposed to preeclampsia.
BBB in vitro analysis
Using human brain endothelial cells, we want to analyze the deleterious effect of circulating factors over the blood brain barrier (BBB) in women who had preeclampsia. The underling mechanism are focused in the understanding of the role of vascular endothelial growth factor in these alterations.